Publications

"Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity"

Jihyeon Yu*, Ju-Chan Park*, Heesoo Uhm, Yong-Woo Kim, Hyeon Woo Im, Sangsu Bae#

Advanced Science

"Therapeutic applications of genome editing tools for genetic diseases"

Ju-Chan Park, Sangsu Bae#

Journal of Electrodiagnosis and Neuromuscular Diseases

"AI-generated MLH1 small binder improves prime editing efficiency"

Ju-Chan Park*, Heesoo Uhm*, Yong-Woo Kim, Ye Eun Oh, Jang Hyeon Lee, Jiyun Yang, Kyoungmi Kim, Sangsu Bae#

Cell

"Current status of genome editing technologies: special issue of BMB reports in 2024"

Ju-Chan Park, Sangsu Bae#

BMB Reports

"Prion-like domain mediated phase separation of ARID1A promotes oncogenic potential of Ewing's sarcoma"

Yong Ryoul Kim*, Jaegeon Joo*, Hee Jung Lee, Chaelim Kim, Ju-Chan Park, Young Suk Yu, Chang Rok Kim, Do Hui Lee, Joowon Cha, Hyemin Kwon, Kimberley M Hanssen, Thomas G P Grünewald, Murim Choi, Ilkyu Han, Sangsu Bae, Inkyung Jung#, Yongdae Shin#, Sung Hee Baek#

Nature Communications

"Enhancing Genome Editing in hPSCs through Dual Inhibition of DNA Damage Response and Repair Pathways"

Ju-Chan Park*, Yun-Jeong Kim*, Gue-Ho Hwang, Chan Young Kang, Hyuk-Jin Cha#

Nature Communications

"Transition substitution of desired bases in human pluripotent stem cells with base editors: A step-by-step guide"

Ju-Chan Park, Keun-Tae Kim, Hyeon-Ki Jang, Hyuk-Jin Cha#

International Journal of Stem Cells

"MutSα and MutSβ as size-dependent cellular determinants for prime editing in human embryonic stem cells"

Ju-Chan Park, Yun-Jeong Kim, Jun Hee Han, Dayeon Kim, Mihn Jeong Park, Jumee Kim, Hyeon-Ki Jang, Sangsu Bae, Hyuk-Jin Cha#

Molecular Therapy – Nucleic Acids

"Gene editing with 'pencil' rather than 'scissor' in human pluripotent stem cells"

Ju-Chan Park, Mihn Jeong Park, Seung-Yeon Lee, Dayeon Kim, Keun-Tae Kim, Hyeon-Ki Jang, Hyuk-Jin Cha#

Stem Cell Research & Therapy

"High expression of uracil DNA glycosylase determines C to T substitution in human pluripotent stem cells"

Ju-Chan Park*, Hyeon-Ki Jang*, Jumee Kim, Jun Hee Han, Youngri Jung, Keuntae Kim, Sangsu Bae#, Hyuk-Jin Cha#

Molecular Therapy – Nucleic Acids

"Multiple isogenic GNE-myopathy modeling with mutation specific phenotypes from human pluripotent stem cells by base editors"

Ju-Chan Park*, Jumee Kim*, Hyun-Ki Jang, Seung-Yeon Lee, Keun-Tae Kim, Eun-Ji Kwon, Seokwoo Park, Hyun Sik Lee, Hyewon Choi, Seung-Yeol Park, Hee-Jung Choi, Soon-Jung Park, Sung-Hwan Moon, Sangsu Bae, Hyuk-Jin Cha#

Biomaterials

"Safe scarless cassette-free selection of genome-edited human pluripotent stem cells using temporary drug resistance"

Keun-Tae Kim*, Ju-Chan Park*, Hyeon-Ki Jang*, Haeseung Lee, Seokwoo Park, Jumee Kim, Ok-Seon Kwon, Young-Hyun Go, Yan Jin, Wankyu Kim, Jeongmi Lee, Sangsu Bae, Hyuk-Jin Cha#

Biomaterials

"Selective Elimination of Culture-Adapted Human Embryonic Stem Cells with BH3 Mimetics"

Seung-Ju Cho*, Keun-Tae Kim*, Ho-Chang Jeong, Ju-Chan Park, Ok-Seon Kwon, Yun-Ho Song, Joong-Gon Shin, Seungmin Kang, Wankyu Kim, Hyoung Doo Shin, Mi-Ok Lee, Sung-Hwan Moon#, Hyuk-Jin Cha#

Stem Cell Reports